HFC refrigerant blend for R-22 retrofit applications. Provides improved efficiency and capacity.

Freon™ NU‑22B™ (R‑422B) – Effortless R‑22 Retrofit Refrigerant

Upgrade your existing R‑22 systems without downtime or overhaul with Freon™ NU‑22B™ (R‑422B) — the reliable, high-performance solution embraced by HVAC technicians worldwide.

🌱 Performance & Compatibility at a Glance

HFC Blend – Zero Ozone Depletion

R‑422B is a non-ozone-depleting hydrofluorocarbon blend composed of R‑125, R‑134a, and R‑600a

Seamless Drop-In Replacement for R‑22

Mimics R‑22’s pressure-temperature behavior with <10% capacity loss, preserving system efficiency

Johnstone Supply

Freon

+1

Refrigerant HQ

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ASHRAE A1 Safety Classification

Non-toxic, non-flammable at atmospheric pressure — safe for technician and end-user environments

🔧 Retrofit Made Easy

No Oil Change Needed

Compatible with mineral oil, alkylbenzene, POE, and PAG — typically avoids the need for oil conversion

Direct Expansion Systems Ready

Designed for TXV, piston, and capillary systems; ideal for residential AC as well as commercial rooftop units and chillers

✅ Technical Highlights

Feature Details

Blend Composition R‑125 / R‑134a / R‑600a (zeotropic)

Ozone Depletion Potential (ODP) 0 — environmentally responsible

Temperature Glide Moderate — requires liquid charging

Capacity Difference vs R‑22 Minimal (<10%), ensuring high performance

🛠️ Ideal Applications

Residential & Commercial AC Systems

Light & Medium Temperature Refrigeration

Walk-in Coolers, Rooftop Units, Packaged Terminals, Non-Flooded Chillers

💼 Why Install NU‑22B?

Cost-Effective Retrofits – No costly oil change or component swaps

Reliable & Safe – Same safety and performance parameters as R‑22

EPA Compliant – Zero ODP, HFC alternative approved under current regulations

Shelf-Ready – Sold in 25 lb (≈11.3 kg) reusable cylinders, DOT-approved and ready-to-use

Applications

  • Air Conditioning

  • Refrigeration

  • Heat Pumps

Use Cases & Compatibility — Freon™ NU-22B™ (R-422B)

Freon™ NU-22B™ (R-422B) is a HFC refrigerant widely used across residential, commercial, and industrial HVAC-R systems. It is compatible with a broad range of equipment from major manufacturers and is suitable for both new installations and retrofit applications.

  • Commercial rooftop HVAC units
  • Split system air conditioners
  • Industrial chillers and cooling systems
  • Automotive air conditioning systems
  • Refrigerated transport and cold storage
  • Supermarket refrigeration systems
  • Air Conditioning
  • Refrigeration
  • Heat Pumps

Complete Specifications — Freon™ NU-22B™ (R-422B)

Specification Value
SKU / Part Number R422B-25LB
Brand Freon™
Category HFC
Chemical Formula R-125/R-134a/R-600a (55/42/3)
CAS Number 12992-48-6
UN Number UN3163
Hazard Class 2.2
EPA Approved Yes
Availability In Stock

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Freon™ NU-22B™ (R-422B) — Whol...

$95.00